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Safi Bahcall

The most important breakthroughs come from “loonshots”—and they need to be nurtured.

Award-Winning Biotech Entrepreneur | Author of Loonshots

Contact Safi For Booking
Safi Bahcall | Award-Winning Biotech Entrepreneur | Author of Loonshots
Lavin Exclusive Speaker

In his instant Wall Street Journal bestselling book Loonshots, Safi Bahcall reveals a surprising new way of thinking about innovation and group dynamics, challenging everything we thought we knew about radical breakthroughs. In talks based on his book—which Nobel Laureate Daniel Kahneman calls “Not to be missed by anyone who wants to understand how ideas change the world”—Bahcall shows how we can stoke innovation, create better leaders, and support “loonshots”: the imperfect but ingenious ideas that have the potential to change the world.

As a consultant at McKinsey & Company, and co-founder and CEO of Synta Pharmaceuticals, Safi Bahcall spent nearly two decades of his life bringing big, innovative ideas to fruition. Frequently, this meant assessing and developing loonshots—the widely dismissed ideas whose champions are often written off as crazy. Along the way, he noticed the obstacles that innovators came up against, which seemed to stem from “the mysteries of group behavior.” As he dynamically explains in his book Loonshots, small changes in the structure of a company, rather than in its culture, can transform the behavior of the distinct groups involved, allowing innovation to flourish. Already a Wall Street Journal bestseller, Loonshots was recently dubbed a must-read "for people and organizations who are trying to increase their ability to catalyze more innovation" by Forbes magazine.


“A wonderful book that explores the beauty, quirkiness and complexity of ideas, Loonshots will both educate and entertain you. If you care about ideas—especially new and out-of-the-box ones—you need to read this book.”

— Siddhartha Mukherjee, Pulitzer Prize-winning author of The Emperor of All Maladies

In his talks, Bahcall shows how the science of phase transitions—think water becoming ice—suggests a useful new way of nurturing radical breakthroughs. He explains the mystery of why good teams—even those with excellent people and the best intentions—can kill great ideas. With humor, history, and a dash of physics, Bahcall offers audiences the tools to become initiators of innovative surprise rather than witnesses to it. 


Bahcall is a physicist and biotech entrepreneur who once worked with President Obama’s Council of Advisors on Science and Technology. After spending three years as a consultant for McKinsey, Bahcall co-founded the biotechnology company Synta Pharmaceuticals, where he helped develop new drugs for cancer treatment. He led Synta’s IPO and served as its CEO for 13 years, during which he was named the Ernst & Young New England Biotechnology/ Pharmaceutical Entrepreneur of the Year. Business Insider, Inc. Magazine, and The Washington Post all included Loonshots, his first book, in their Top 10 and Must-Read booklists of 2019.

Speech Topics

Loonshots How to Nurture the Crazy Ideas That Win Wars, Cure Diseases, and Transform Industries
Drugs that save lives, like technologies that transform industries, often begin with inventors championing crazy ideas—aka “loonshots.” But large groups of people are needed to translate those ideas into products that work, says Safi Bahcall. When teams with the means to develop innovative ideas reject them, those breakthroughs remain buried inside labs or trapped underneath the rubble of failed companies. So how can companies, teams, or projects go from failing to thriving? The people are the same, the culture is the same, yet somehow they become different, says Bahcall. Using examples that range from the spread of fires in forests to the stories of thieves and geniuses and kings, Bahcall shows audiences how to understand the behavior of companies and the fate of empires, distilling these insights into lessons for creatives, entrepreneurs, and visionaries everywhere. 
Corporate Culture
Empowering HR Harnessing the Motivational Power of the Middle

Safi Bahcall forecasts a future where we have a shift in mindset and recognize the enormous strategic potential HR could unlock in stagnating companies. It’s a department that needs to be elevated and expanded—and there are already incredible opportunities to reshape its functionality and refocus the energy of human resource professionals. For instance, the current climate of managers making all the decisions regarding bonuses and raises places company culture firmly in the political—making innovation less likely, as employees are afraid to experiment. But what if there was a nonpartisan professional who’s specific functionality was to assess performance, detached from office politics? Or, since we have CFOs and CEOs, why not have a Chief Incentives Officer?


As leaders, it can be difficult to accurately assess the value of an employee’s contributions, especially if their work itself isn’t exactly in your field. That’s why, Bahcall argues, having a more involved, yet neutral party make those kinds of calls would spark real change. They could also help increase employee-project skill fit; and find the right balance of intrinsic, personal motivators and an external reward system to enhance productivity—and positivity. How can we enable HR to be metaphorically bilingual in the workplace: able to communicate with the creatives and the corporate intuitively and impartially—and relay their needs back to each other in terms they will understand? It’s time to move past the outdated compensation and communication models of the 20th century and into methods that reflect our expanded understanding of what makes people tick: and Bahcall is just the expert to get you there.